Richard Alan Blatchly

Chemistry Department
Keene State College
Keene, NH  03435
(603) 358-2564

Professional Overview

My teaching assignments at Keene State College are primarily in Organic Chemistry, although I have taught courses from the introductory level to advanced instrumental analysis.

My research work involves the synthesis and analysis of foldamers.

I will be on sabbatical leave from July, 2004 to July 2005, visiting the European Institute for Chemistry and Biology (IECB) in Bordeaux, France. There, I will be working with the groups of Ivan Huc, Reiko Oda , Michel Laguerre, and others.

Education and Collaborations



Field of Study



Williams College





Columbia University

Ph. D.
(K. Nakanishi)




Univ. Calif., San Francisco

Post-doctoral research fellow
(G. Kenyon)



4. Pennsylvania State University

Visiting Professor
(S. Benkovic)

Chemistry 1987-8
5. University of Massachusetts Collaboration
(G. Tew)
Polymer Science and Engineering 2002-present


R. A. Blatchly  and G. N. Tew, J. Org. Chemistry , 68(23), 8780-5 (2003).  “Theoretical Study of Helix Formation in Substituted Phenylene Ethynylene Oligomers”    

Ticora V. Jones, Richard A. Blatchly† and Gregory N. Tew,  Org. Lett., 5(18): p. 3297-9 (2003).  “Synthesis of Alkoxy-Substituted Ortho-Phenylene Ethynylene Oligomers”

P. Yuan, M. R. Driscoll, D. E. Hansen, and R. A. Blatchly, Tetrah. Lett., 35, 6195-6198 (1994).  The Synthesis of Cyclobutanol-Containing Dipeptide Analogs.

J. Inglese, R. A. Blatchly, S. J. Benkovic, J. Med. Chem., 32, 937-8 (1989).  A Multisubstrate Adduct Inhibitor of GAR Transformylase Possessing a Picomolar Dissociation Constant.

Inglese, R. A. Blatchly, S. J. Benkovic, US Patent #269510.  Transition state analog inhibitors of glycinamide ribonucleotide transformylase for use as anti-gout or anti-cancer agents.

Richard A. Blatchly, Timothy R. Allen, Dirk T. Bergstrom and Yuji Shinozaki, J. Chem. Ed., 66, 965-967 (1989).  Microscale Synthesis and Analysis of a Dipeptide.

Richard A. Blatchly, Michael A. Greeley, and J. Hodge Markgraf, Heterocycles, 29, 2345-51 (1989).  The Skraup Reaction of 3,4-Dihaloanilines.

O. Muto, F. Tokunaga, T. Yoshizawa, V. Kamat, R. A. Blatchly, V. Balogh-Nair, and K. Nakanishi, Biochim. Biophys. Acta, 766, 597-602 (1984).  Photochemical Reaction of 7,8-Dihydrorhodopsin at Low Temperatures.

R. A. Blatchly and K. Nakanishi, Methods in Enzymology, 88, 491-6 (1982).  Use of HPLC to Separate and Identify Retinals.

J. H. Markgraf, R. A. Blatchly, B. M. Peake and A. S. Huffadine, J. Chem. Eng. Data, 27, 473-4 (1982).  Basicities of Selected Quinoxalines.

R. A. Blatchly, J. D. Carriker, V. Balogh-Nair, and K. Nakanishi, J. Am. Chem. Soc.,102, 2495-6 (1980).  Adamantyl Allenic Rhodopsin.  Leniency of the Ring Binding Site on Bovine Opsin.

R. A. Blatchly, Ph.D. Thesis, Columbia Univ., NY, NY (1981).  I:  Allenic Rhodopsin--Probing the Binding Site of Bovine Rhodopsin.  II: Low Temperature and Infrared Spectroscopy of Bovine Rhodopsins.

J. H. Markgraf, J. H. Antin, F. J. Walker and R. A. Blatchly, J. Org. Chem., 44, 3261 (1979).  6,7-Dihydrocyclobuta[g]quinoline.


Honors and Societies:

Member American Chemical Society, 1976 to present

Member American Association for the Advancement of Science, 1981 to present


Bicycle riding, choral singing, reading. We have at least one cat more than we need, and also have an energetic and enthusiastic springer spaniel (we don't hunt, but enjoy long forays into the woods). What is is that they say about pets resembling their owners, or vice versa?